Brimonidine Tartrate CAS 70359-46-5, Best price from China supplier factory
TNJ Chemical is a China factory, supplier and manufacturer of Brimonidine Tartrate CAS 70359-46-5 with plant site in Feidong Anhui Province. We are certified by GMP, ISO and SGS organization and specialize in chemical since from 2001. To buy bulk quantity Brimonidine Tartrate CAS 70359-46-5 at wholesale discounted price, please send your price inquiry to sales@tnjchem.com
Application & Function
This product is a relatively selective α2 adrenergic receptor agonist for ophthalmology, with a high degree of selectivity for α2 receptors. This product has good retinal biological activity and neuroprotective functions. Compared with other α2-adrenergic receptor agonists, this product is less fat-soluble, not easy to cross the blood-brain barrier, and does not produce sedation, hypotension and other central disorders reaction. It can reduce the production rate of aqueous humor and increase uveoscleral outflow, resulting in a drop in intraocular pressure. It has antihypertensive effect on glaucoma and normal eyes, and has little effect on cardiovascular system and respiratory system function.
Specification
| Appearance | White or slightly yellowish or slightly brownish powder |
| Identification | A.Specific optical rotation |
| B.Infrared absorption spectrophotometry | |
| Solubility | Soluble in water ,practically insoluble in anhydrous ethanol and in toluene |
| Specific Optical Rotation | +9.0°-- +10.5° |
| Loss on drying，% | ≤0.5 |
| Sulfated Ash,% | ≤0.2 |
| Heavy metal,ppm | ≤20 |
| Related substance,% | Specified impurities: |
| N-(imidazolidin2ylidene)quinoxalin-6-amine≤0.1 | |
| 5-bromoquinoxalin-6-amine≤0.1 | |
| Quinoxalin-6-amine≤0.1 | |
| 1-（5-bromoquinoxalin-6-yl)thiourea≤0.1 | |
| 2-（5-bromoquinoxalin-6-yl)guanidine≤0.1 | |
| 5-bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine≤0.1 | |
| 1-(2-aminoethyl)-3-（5-bromoquinoxlin-6yl）urea≤0.1 | |
| Unspecified impurities≤0.1 | |
| Total≤0.2 | |
| Assay(On dried basis),% | 99.0-101.0 |
